一、个人简介
主要从事水产动物内分泌及代谢和水产动物肠道益生菌研究，对功能基因进行发掘，研究其对水产动物生长、糖脂代谢、免疫的调控机制。近五年来主持国家自然科学基金、河南省自然科学基金、河南省科技攻关项目等5项，在《Frontiers in Immunology》、《Aquaculture》等SCI期刊及国内重要期刊发表及参与发表学术论文50余篇，授权发明专利4项。
二、通讯地址
地址：河南省新乡市牧野区建设东路46号
E-mail: ygk5210207@126.com
电话：15090322075
三、教育背景
博士(2012/09-2017/12): 中山大学，生命科学学院，水生生物学专业
学士(2008/09-2012/06): 佳木斯大学，生命科学学院，生物技术专业
四、工作经历
2018/03- 至今：河南师范大学水产学院，讲师
五、承担课程
生物化学、分子营养学、水产动物营养与饲料实验
六、研究方向
1. 水产动物内分泌及代谢
2. 益生菌功能基因的发掘及应用
七、科研项目
1) Amuc_1100介导TLR2/c-Jun/GIP通路调控大口黑鲈糖代谢机制研究，国家自然科学基金青年项目 (32303020)，主持
2) GIP/GIPR调控草鱼脂肪代谢的研究，河南省科技攻关项目 (202102110259)，主持
3) GIP/GIPR对草鱼脂肪沉积的调控机制研究，河南省自然科学基金 (212300410174)，主持
4) Irisin对鲤肝脏糖脂代谢的调控机制研究，河南省高等学校重点科研项目 (20A240005)，主持
5) 胰岛素对草鱼肝脏糖稳态的调控研究，河南省科技攻关项目 (192102110193)，主持
八、代表性研究成果（发表论文出版刊物授权专利）
1) Guokun Yang, Chengquan Li, Sunan Wang, Xiaomin Liang, Boya Yang,Yanmin Zhang, Xindang Zhang, Xulu Chang, Xiaolin Meng*.Molecular characterization of the grass carp bscl2 gene and its expression response to lipid accumulation, nutritional status, insulin and glucagon, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2024, 270, 110931.
2) Guokun Yang, Boya Yang, Sunan Wang, Xiaomin Liang, Chengquan Li, Yanmin Zhang, Xindang Zhang, Xulu Chang, Xiaolin Meng*.Cloning grass carp (Ctenopharyngodon idella) ccdc3 and its expression affected by nutrition state, insulin, and glucagon, Journal of Fish Biology, 2023, 15614.
3) Guokun Yang, Aixia Jiang, Huimin Cai, Fu You, Shengkui Wu, Yanmin Zhang, Xindang Zhang, Yawei Shen, Xulu Chang, Wenpan Hu, Keke Li, Xiaolin Meng*. Supplementation with Akkermansia muciniphila improved glucose metabolism disorder in common carp (Cyprinus carpio L.), Aquaculture, 2023, 2023: 739465.
4)Guokun Yang, Xiaomin Liang, Shuangyang Xu, Huimin Cai, Limei Ma, Xulu Chang, Yanmin Zhang, Liping Yang, Xiaolin Meng*. Molecular identification of Igf3 and its roles in grass carp (Ctenopharyngodon idella). Aquaculture 2022, 548.
5) Guokun Yang, Xiaomin Liang, Chaobin Qin, Liping Yang, Yanmin Zhang, Ronghua Lu, Xiao Yan, Xiaolin Meng, Guoxing Nie*. Molecular cloning, tissue distribution and functional characterization of glucose-dependent insulinotropic peptide (GIP) gene in Ctenopharyngodon idella. Aquaculture 2022, 548.
6) Guokun Yang, Xiaomin Liang, Yanle Jiang, Chengquan Li, Yanmin Zhang, Xindang Zhang, Xulu Chang, Yawei Shen, Xiaolin Meng*. Molecular Characterization of Grass Carp GIPR and Effect of Nutrition States, Insulin, and Glucagon on Its Expression, Aquaculture Nutrition, 2022, 2022: 4330251.
7) Guokun Yang, Xiaomin Liang, Yanle Jiang, Chengquan Li, Jihong Hu, Yanmin Zhang, Xindang Zhang, Xulu Chang, Wenpan Hu, Keke Li, Xiaolin Meng*. Myonectin in grass carp (Ctenopharyngodon idella): Molecular cloning and effect of nutrition state, insulin and glucagon on myonectin expression, Aquaculture Reports, 2022, 26(2022): 101306.
8) Guokun Yang, Xiaomin Liang, Jihong Hu, Chengquan Li, Wenpan Hu, Keke Li, Xulu Chang, Yanmin Zhang, Xindang Zhang, Yawei Shen, Xiaolin Meng*. Feeding tea polysaccharides affects lipid metabolism, antioxidant capacity and immunity of common carp (Cyprinus carpio L.), Frontiers in Immunology, 2022, 13: 1074198.
9) Guokun Yang, Wenli Zhao, Chaobin Qin, Liping Yang, Xiaolin Meng, Ronghua Lu, Xiao Yan, Xianglin Cao, Yanmin Zhang, Guoxing Nie*. Molecular identification of grass carp igfbp2 and the effect of glucose, insulin, and glucagon on igfbp2 mRNA expression, Fish Physiology and Biochemistry 2020, 46: 1469-1482.
10) Guokun Yang,Wenli Zhao, Chaobin Qin, Liping Yang, Xiaolin Meng, Ronghua Lu, Xiao Yan, Xianglin Cao, Yanmin Zhang, Guoxing Nie*, Igfbp3 in grass carp (Ctenopharyngodon idellus): Molecular identification and mRNA expression under glucose, insulin and glucagon, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2020, 242: 110394.
11) Guokun Yang,Beichen Chen, Caiyun Sun, Xi Yuan, Yazhou Zhang, Jingkai Qin, Wensheng Li*, Molecular identification of grouper Igfbp1 and its mRNA expression in primary hepatocytes under Gh and insulin, General and Comparative Endocrinology, 2019, 281: 137-144.
12)Guokun Yang, Qinqin Song, Caiyun Sun, Jingkai Qin, Jirong Jia, Xi Yuan, Yazhou Zhang, Wensheng Li*. Ctrp9 and adiponectin receptors in Nile tilapia (Oreochromis niloticus): Molecular cloning, tissue distribution and effects on reproductive genes, General and Comparative Endocrinology, 2018, 265: 160-173.
13)Guokun Yang, Chaobin Qin, Bin Wang, Jirong Jia, Xi Yuan, Caiyun Sun, Wensheng Li*. Molecular identification and functional analysis of CTRP9 in Epinephelus coioides. Journal of Molecular Endocrinology, 2017, 58(4): 179-191.
14) 张新党，孟晓林，杨国坤，张艳敏，常绪路，一种克氏原螯虾的池塘精养方法，2023.05.05，中国，ZL202210564890.3
15) 秦超彬，赵文丽，杨国坤，聂国兴，杨丽萍，孟晓林，卢荣华，草鱼AdiponectinA基因、编码蛋白及其应用，2022.11.08，中国，ZL201910522917.0
16) 李文笙，杨国坤，斜带石斑鱼insulin基因、编码蛋白及其应用, 2021.07.27,中国, ZL201711001284.6
17) 李文笙，杨国坤，秦超彬，斜带石斑鱼ctrp9基因、编码蛋白及其应用， 2016.06.15，中国, ZL201410380895.6
