刘彦礼，博士，新乡医学院干细胞与生物治疗技术研究中心副教授，新乡高新区中源干细胞研究院院长。工作经历：2013.07–2017.04新乡医学院生命科学技术学院干细胞与生物治疗技术研究中心讲师；2017.09–2018.09柏林自由大学化学与生物化学研究所访问博士后；2017.04–至今新乡医学院生命科学技术学院干细胞与生物治疗技术研究中心副教授；目前主要从事子宫内膜干细胞的生物学特性及其临床应用研究。重在完善并规范从经血样本中分离获得子宫内膜干细胞的方法，依托合作研究院建立间充质干细胞GMP生产流程，为经血源子宫内膜干细胞的临床应用提供稳定的细胞来源，同时为基于经血源子宫内膜干细胞大数据分析评估女性生殖健康奠定基础。

承担项目课题：

1.国家自然科学基金青年科学基金项目，《B淋巴细胞介导超抗原SEC2活化鸡T淋巴细胞及其促进体液免疫的机制研究》，31502045，2016/01-2018/12，21万元，结题，主持；

2.国家自然科学基金面上项目，《经血源性子宫内膜干细胞对中枢神经系统自体免疫疾病的治疗和机制研究》，2017/01-2020/12，57万元，在研，参与；

3.新乡市科技重大专项，《子宫内膜干细胞的技术开发与应用研究》，2017/06-2018/12，100万元，在研，参与。

4.中央引导地方科技发展专项，《基于子宫内膜干细胞探索子宫内膜异位症/腺肌症发病机制及早期诊断方法》2020/04-2022/04，70万元，在研，主持。

5.河南省科技攻关项目《经血源子宫内膜干细胞通过调节Treg细胞改善1型糖尿病胰岛β细胞功能的作用机制研究》，212102310611，2021/01-2022/12，在研，主持；

6.新乡市科技攻关项目，《经血源子宫内膜干细胞通过免疫调控改善1型糖尿病胰腺炎发生发展的作用机制研究》，GG2020009，2021/01-2022/12，3万元，在研，主持；

主要成果：

1.ZhangS, Sun Y, Jiang D, Chen T, Liu R, Li X, Lu Y, Qiao L, Pan Y^*,Liu Y^*,Lin J. Construction and Optimization of an Endometrial Injury Modelin Mice by Transcervical Ethanol Perfusion. Reprod Sci,2021;28(3):693-702.

2.LiuY, Liang S, Yang F, Sun Y, Niu L, Ren Y, Wang H, He Y, Du J, Yang J,Lin J^*.Biological characteristics of endometriotic mesenchymal stem cellsisolated from ectopic lesions of patients with endometriosis. StemCell Res Ther. 2020, 11(1):346. 

3.LiuY, Zhang Z, Yang F, et al. The role of endometrial stem cells in thepathogenesis of endometriosis and their application to its earlydiagnosis†. Biol Reprod. 2020;102(6):1153-1159.

4.YuliangSun, Yakun Ren, Fen Yang, Yanan He, Shengying Liang, Lihong Guan,Fangfang Cheng, Yanli Liu^*,Juntang Lin^*.High-yield isolation of menstrual blood-derived endometrial stemcells by direct red blood cell lysis treatment. Biology open, 2019,8(5).

5.YananHe, Yuliang Sun, Yakun Ren, Liang Qiao, Rui Guo, Jiang Du, XinxingZhu, Yanli Liu ^*,Juntang Lin. The T cell activating properties and antitumour activityof Staphylococcal Enterotoxin-like Q. Medical microbiology andimmunology, 2019, 208(6):781-792.

6.YanliLiu, Rongcheng Niu, Wenzhong Li, Juntang Lin^*,Christof Stamm, Gustav Steinhoff, Nan Ma. Therapeutic potential ofmenstrual blood-derived endometrial stem cells in cardiac diseases.Cellular and Molecular Life Sciences, 2019, 76(9):1681-1695.

7.ZhuX^#,Liu Y^#,Yu J, et al. LncRNA HOXA-AS2 represses endothelium inflammation byregulating the activity of NF-κB signaling. Atherosclerosis2018;281:38-46.(共同一作)

8.YanliLiu, Rongcheng Niu, Fen Yang, Yan Yan, Shengying Liang, Yuliang Sun,Ping Shen, Juntang Lin^*.Biological characteristics of human menstrual blood‐derivedendometrial stem cells. Journal of cellular and molecular medicine,2018, 22(3): 1627-1639.

9.YanliLiu, Fen Yang, Shengying Liang, Qing Liu, Sulei Fu, Zhenyu Wang,Ciqing Yang, Juntang Lin^*.N-Cadherin Upregulation Promotes the Neurogenic Differentiation ofMenstrual Blood-Derived Endometrial Stem Cells. Stem cellsinternational, 2018, 2018: 3250379.

10.YanliLiu, Sulei Fu, Rongcheng Niu, Ciqing Yang, Juntang Lin^*,Transcriptional activity assessment of three different promoters formouse in utero electroporation system, Plasmid, 2014, 74: 52-58.

11.YanliLiu, Mingkai Xu, Xu Li, Jian Sun, Chenggang Zhang, Huiwen Zhang^*,The construction of a bifunctional fusion protein consisting of SEC2and EGFP, Biotechnology and Applied Biochemistry, 2014, 61(5):565-571

12.YanliLiu, Mingkai Xu^*,Huiwen Zhang, Xu Li, Zhencheng Su, Chenggang Zhang, SEC2-inducedsuperantigen and antitumor activity is regulated through calcineurin,Applied Microbiology and Biotechnology, 2013, 97(22): 9695-9703

YanliLiu, M. Xu, Z. Su, Y. Cai, G. Zhang, H. Zhang ^*,Increased T-cell stimulating activity by mutated SEC2 correlates withits improved antitumour potency, Letters in Applied Microbiology,2012, 5(55): 362-369