 | | 卢雁，男，1953年5月生，教授、博士生导师、河南师范大学特聘教授、教学名师，兰州大学兼职教授、博士生导师。国务院政府特殊津贴专家、物理化学重点学科学术带头人、物理化学国家级特色专业带头人、物理化学省精品课程带头人、河南省学位点建设和研究生教育工作先进个人、河南省基础研究先进个人。现任中国化学会化学热力学与热分析专业委员会委员、理事，河南省化学会常务理事兼物理化学专业委员会主任。 | |
| | 学习与工作经历： 1973.09-1976.06 新乡师范学院化学系 化学专业学习 1976.07-1978.08 新乡市化工局工人大学 教师 1978.09-1981.06 新乡师范学院 物理化学专业研究生，获硕士学位 1988.11-1989.11 英国Bristol大学高访学者 1995.02-1995.08 英国Sheffield大学高访学者 1982.01至今 河南师范大学化学化工学院 讲师、副教授、教授、特聘教授 主讲课程： 物理化学，物理化学研究进展，化学生物学进展，计算机与模拟化学进展，统计热力学 研究领域与兴趣： 1. 溶液热力学 2. 生物热力学 3. 生物纳米技术及纳米毒理研究 近年来主持的主要科研项目: 1.国家自然科学基金（29773011）：蛋白质空间结构中所含基团相互作用的热力学研究 2.国家自然科学基金（20443002）：蛋白质化学变性机理的热力学和波普研究 3.国家自然科学基金（20673034）：蛋白质相互作用与变性热力学参数的研究 4.国家自然科学基金（21173071）：贵金属纳米粒子与蛋白质相互作用的热力学与谱学研究 5.教育部高等学校博士点基金 (20060476001)：蛋白质化学变性机理的热力学与谱学研究 6.教育部高等学校博士点基金 (20114104110002)：蛋白质与金、银纳米粒子相互作用的热力学研究。 代表性论文： 在Biosensor & Bioelectronics, J Phys Chem B, Langmuir等SCI源期刊发表论文120多篇，论文被引用600余次。 1. Yan Lu*, Gongke Wang, Lixia Wang, Dejun Chen.. Determination of the concentration and the average number of gold atoms of gold nanoparticle by osmotic pressure. Langmuir, 2012, 38: 9282–9287. 2. Yan Lu*, Xiang Li, GongKe Wang, Wen Tang. A highly sensitive and selective optical sensor for Pb2+ by using conjugated polymers and label-free oligonucleotides. Biosensors and Bioelectronics, 2013, 39: 231–235. 3. Gongke Wang, Changling Yan, Dongchao Wang, Dan Li, Yan Lu*. Specific binding of a dihydropyrimidinone derivative with DNA: Spectroscopic, calorimetric and modeling investigations. Journal of Luminescence, 2012, 132(1): 1656–1662. 4. Gongke Wang, Xiang Li, Xuelian Ding, Dongchao Wang, Changling Yan, Yan Lu*. Exploring the mechanism of interaction between 5-(Ethoxycarbonyl)-6-methyl-4-(4-methoxyphenyl)-3,4-dihydropyrimidin-2(1H)-one and human serum albumin: spectroscopic, calorimetric and molecular modeling studies. Journal of Pharmaceutical and Biomedical Analysis, 2011, 55(5): 1223–1226. 5. Gongke Wang, Dongchao Wang, Xiang Li，Yan Lu*. Exploring the binding mechanism of dihydropyrimidinones to human serum albumin: Spectroscopic and molecular modeling techniques. Colloids and Surfaces B: Biointerfaces, 2011, 84(1): 272–279. 6. Yan Lu*, Gongke Wang, Juan Lv, Guisheng Zhang, Qingfeng Liu. Study on the Interaction of an Anthracycline Disaccharide with DNA by Spectroscopic Techniques and Molecular Modeling. Journal of Fluorescence, 2011, 21(1): 409–414. 7. Gongke Wang, Lixia Wang, Xiaoxiao Hao, Wen Tang, Yunlai Wang, Yan Lu*. Binding of quercetin to Lysozyme as probed by spectroscopic analysis and molecular simulation. Journal of Fluorescence, 2011, 21(5): 1879–1886. 8. Yan Lu*, Gongke Wang, Wen Tang, Xiaoxiao Hao, Meihua Xu, Xiang Li. Study on the interaction of amino phosphine ester derivatives with DNA by spectroscopy, modeling and calorimetry. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2011, 82(1): 247–252. 9. Yan Lu,* Meihua Xu, Gongke Wang, Yun Zheng. Interaction of diethyl aniline methylphosphonate with DNA:Spectroscopic and isothermal titration calorimetry. Journal of Luminescence, 2011，131(5): 926-930. 10.Yan Lu*, Gongke Wang, Xiumin Lu, Juan Lv, Meihua Xu, Weiwei Zhang. Molecular mechanism of interaction between norfloxacin and trypsin studied by molecular spectroscopy and modeling. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2010, 75(1): 261–266. 11.Yan Lu*, Juan Lv, Guisheng Zhang, Gongke Wang, Qingfeng Liu. Interaction of an anthracycline disaccharide with ctDNA: Investigation by spectroscopic technique and modeling studies. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2010, 75(5): 1511–1515. 12.Yan Lu, Qingqin Feng, Fengling Cui, Weiwei Xing, Guisheng Zhang, Xiaojun Yao. Interaction of 3'-azido-3'-deamino daunorubicin with human serum albumin: Investigation by fluorescence spectroscopy and molecular modeling methods. Bioorganic & Medicinal Chemistry Letters, 2010, 20: 6899–6904. 13.Yan Lu*, Gongke Wang, Chang-Ling Yan, et.al. Study on the binding of fluoride, bromide and iodide to ovalbumin by using ion-selective electrodes. Journal of Biochemistry. 2009, 145: 309–314. 14.Gongke Wang, Yan Lu*, Chang-Ling Yan. Study on the Binding of Chloride Ion to Hemoglobin Using Electromotive Force Method. Journal of Chinese Chemical Society-Taipei. 2009, 56: 368–373. 15.Yan Lu, Fengling Cui, Jing Fan,YingYang, Xiaojun Yao, Jianping Li. Interaction of human serum albumin with N-(4-ethoxyphenyl)-N -(4-antipyrinyl) thiourea using spectroscopies and molecular modeling method. Journal of Luminescence. 2009, 129: 734-740. 16.Yan Lu *, Chang-Ling Yan, Shu-Yan Gao. Preparation and recognition of surface molecularly imprinted core–shell microbeads for protein in aqueous solutions. Applied Surface Science. 2009, 255: 6061-6066. 17.Yan Lu*, De-Jun Chen, Gong-Ke Wang, Chang-Ling Yan. Study on the interactions of bovine serum albumin in aqueous (NH4)2SO4 solution by osmotic pressure measurements. Journal of Chemical & Engineering Data. 2009, 54: 1975-1980. 18.Yan Lu*, Yun-Lai Wang, Sheng-Hua Gao, Gong-Ke Wang, Chang-Ling Yan, De-Jun Chen. Interaction of quercetin with ovalbumin: Spectroscopic and molecular modeling studies. Journal of Luminescence. 2009, 129: 1048-1054. 19.Yan Lu*, Chang-Ling Yan, Xue-Jing Wang, Gong-Ke Wang. Protein imprinting and recognition via forming nanofilms on microbeads surfaces in aqueous media. Applied Surface Science. 2009, 256: 1341-1346. 20.Changling Yan, Yan Lu*, Shuyan Gao. Coating Lysozyme Molecularly Imprinted Thin Films on the Surface of Microspheres. Journal of Polymer Chemistry, 2007, 45(45): 1911-1919. 21.Jianjun Zhu, Rong Ma, Yan Lu*, George Stell. Dynamic salt effect on intramolecular charge-transfer reactions. Journal of Chemical Physics, 2005, 123: (22): 224505-224505.8. 22.Yan Lu*, Yumin Han, Meiying Liu, Qingtang Cheng. Enthalpic and Volumetic Studies of the Interactions of Propionamide in Aqueous Carboxylic Acid solutions at 298.15K. Thermochemia Acta, 2004，416(1-2): 65-70. 23.Yan Lu*. Enthorpic interaction for α-amino acid with alkali metal halides in water. Chinese Journal of Chemistry, 2004，22(8): 822-826. |