韩娇娜，博士，硕士生导师
Email:2023168@htu.edu.cn
2013.09—2017.07，郑州大学，化学，学士
2017.09—2019.07，郑州大学，化学，硕士
2019.09—2023.06，湖南大学，化学，博士
工作经历：
2023.06—至今，河南师范大学，讲师
主讲课程：
仪器分析、仪器分析实验、分析化学实验、高等分析实验、综合与设计实验、实验设计与数据处理、数据统计与分析
研究领域与兴趣：
生命科学中的新分析方法
功能染料与传感器件的设计及其生物成像与治疗应用
主持项目：
1.河南师范大学博士科研启动费支持课题：基于激活型多色G4荧光探针的癌症成像研究，项目编号：校20240225，2024.01-2026.12
2.河南省高等学校重点科研项目：生物酶与G-四链体协同激活型光敏剂的开发及应用研究，项目编号：25A150013，2024.10-2026.12
3.中国博士后科学基金面上项目：“双钥匙-锁”G-四链体近红外二区探针的构建及其癌症精准成像研究，项目编号：2024M760831，2024.11-2027.07
4.河南省自然科学基金青年科学基金：激活型G-四链体近红外二区荧光探针的构建及其活体肿瘤精准成像研究，项目编号：252300421716，2025.01-2026.12
代表性论文：
1.Jiaona Han, Meng Yang, Yao He, Kui Wang*, Lingyue Zhang, Rui Zhang, Hui Qiao, Yonggang Yang*,and Hua Zhang*, Light-Driven ESIPT-Based Anthraquinone Analogues for Synergistic Fluorescent Self-Reporting and Photodynamic Therapy of Malignant Tumors,Journal of Medicinal Chemistry, 2025, 68, 20814-20826. (SCI一区TOP)
2. Jiaona Han*, Jun Li, Xingyu Luo, Guangfu Feng* and Jiaheng Zhang*, Developments in near-infrared fluorescent probes for G-quadruplexes structures. Coordination Chemistry Reviews, 2024, 520, 216157-216173. (SCI一区TOP)
3.Yue Mou, Yanfei Zhang, Meiyun Chen, Xinru Lin, Jiaheng Zhang*, Jiaona Han* and Xingyu Luo*, Dual-mode aptasensor based on a coumarin–benzothiazole fluorescent and colorimetric probe for label-free and visual detection of ochratoxin A. Sensors and Actuators: B. Chemical, 2024, 408, 135529-135537.(SCI一区TOP)
4. Jiaona Han*, Hanyan Ren, Xingyu Luo*, Jun Li* and Jiaheng Zhang*, Novel dual-color fluorescence probe for monitoring the fluctuation of lysosomal polarity and viscosity during apoptosis, Microchemical Journal, 2024, 207, 111860-111868. (SCI二区)
5. Jiao-Na Han, Caijun Zhong, Mingmin Ge, Shi Kuang* and Zhou Nie*, Engineering fluorescent protein chromophores with an internal reference for high-fidelity ratiometric G4 imaging in living cells,Chemical Science, 2023, 14, 4538-4548. (SCI一区TOP)
6.Jiao-Na Han, Mingmin Ge, Pengfei Chen, Shi Kuang*, and Zhou Nie*, Advances in G-quadruplexes based fluorescent imaging. Biopolymers, 2022, 113, e23528-e23544. (SCI四区)
7.Gui-Xian Kong1, Jiao-Na Han1, Dandan Yang, Jun-Long Niu*, and Mao-Ping Song*, Manganese catalyzed cascade annulations of alkyne-tethered N-alkoxyamides: synthesis of polycyclic isoquinolin-1(2H)-ones, Organic & Biomolecular Chemistry, 2019, 17, 10167-10171.(SCI三区)
8. Jiao-Na Han, Cong Du, Xinju Zhu, Zheng-Long Wang, Yue Zhu, Zhao-Yang Chu, Jun-Long Niu* and Mao-Ping Song*, Cobalt-catalyzed peri-selective alkoxylation of 1-naphthylamine derivatives, Beilstein Journal of Organic Chemistry, 2018, 14, 2090-2097. (SCI三区)