牛慧玉，博士
研究方向：荧光染料的功能化调控及其在生物识别与癌症治疗中的应用
邮箱：2994833638@qq.com
教育经历
(1) 2018.09-2024.12, 河南师范大学, 化学化工学院, 硕博连读
(2) 2014.09-2018.06, 河南师范大学, 化学化工学院, 本科
科研和学术工作经历
（1）2025-01至今，河南师范大学，化学化工学院，讲师
（2）2025.03-2025.09，韩国梨花女子大学，化学纳米科学系，访问学者
主持或参加科研项目情况
(1) 青年科学基金项目（C类）, 22508103, meso位苯基取代BODIPY染料的自组装行为调控与光敏功能强化, 2026.01-2028.12, 在研, 主持
(2) 国家自然科学基金委员会, 联合基金项目, U21A20314, 重度乏氧肿瘤诊疗用光敏染料分子的设计、合成与性能研究, 2022.01-2025.12, 在研, 参与
代表性研究成果
(1) Huiyu Niu, Songnan Wang, Yang Liu, Nana Ma, Shuaiwei Cheng, Beidou Feng, Hyunsun Jeong, Yonggang Yang, Ge Wang, Tony D. James, Juyoung Yoon*, Jonathan L. Sessler*, Hua Zhang*, Naphthalimide-Based Type-I Nano-Photosensitizers for Enhanced Antitumor Photodynamic Therapy: H2S Synergistically Regulates PeT and Self-Assembly, Angewandte Chemie International Edition, 2025, 64, e202512150.
(2) Huiyu Niu; Yang Liu, Yafu Wang, Yonggang Yang, Ge Wang, Tony D James; Jonathan L Sessler*; Hua Zhang*; Photochemical and biological dual-effects enhance the inhibition of photosensitizers for tumour growth, Chemical Science, 2024, 15(20): 7757-7766.
(3) Huiyu Niu, Junwei Liu, Helen M O’Connor, Thorfinnur Gunnlaugsson, Tony D James*, Hua Zhang*, Photoinduced electron transfer (PeT) based fluorescent probes for cellular imaging and disease therapy, Chemcial Society Reviews, 2023, 52(7): 2322-2357.
(4) Yafu Wang, Huiyu Niu, Kui Wang, Liu Yang, Ge Wang, Tony D James, Jiangli Fan*, Hua Zhang*, Fluorescence-plane polarization for the real-time monitoring of transferase migration in living cells, Chemical Science, 2024, 15(39): 16291-16299.
(5) Beidou Feng, Zhe Wang, Xiaoli Zhao, Huiyu Niu, Yafu Wang, Kui Wang, Kai Jiang, Hua Zhang*, Self-Internal Standard Fluorescence for Ultrasensitive Detecting of mtDNA to Evaluate Matrilineal Genetic Defect Levels, Analytical Chemistry, 2024, 96(35): 14125-14132.
(6) Yafu Wang, Huiyu Niu, Kui Wang, Ge Wang, Junwei Liu, Tony D James, Hua, Zhang*, mtDNA-Specific Ultrasensitive Near-Infrared Fluorescent Probe Enables the Differentiation of Healthy and Apoptotic Cells, Analytical Chemistry, 2022, 94(21): 7510-7519.
(7) Beidou Feng, Huiyu Niu, Hongchen Zhai, Congcong Shen, Hua Zhang*, In-situ hydrophobic environment triggering reactive fluorescence probe to real-time monitor mitochondrial DNA damage, Frontiers of Chemical Science and Engineering, 2022, 16: 92-102.
(8) Beidou Feng, Kui Wang, Zhe Wang, Huiyu Niu, Ge Wang, Yuehua Chen, Hua Zhang*, Mitochondrial-Targeted Ratiometric Fluorescent Probe to Monitor ClO − Induced by Ferroptosis in Living Cells, Frontiers in Chemistry, 2022, 10: 909670-909676.
专利
(1) 蒋涛; 王鑫; 仉华; 王亚甫; 冯北斗; 牛慧玉; 赵小丽; 陈长坡 ; 萘衍生物类荧光染料及其制备方法和用途, 2023-03-31, 中国, CN201811011554.6
(2) 仉华; 冯北斗; 牛慧玉; 刘俊维; 姚美焕; 一种无机有机复合二氧化钛量子点的制备方法及其在肿瘤细胞成像检测中的应用, 2020-04-21, 中国, CN201710682857.X
(3) 仉华; 刘俊维; 郭玉明; 王亚甫; 牛慧玉; 程定玺; 含吡唑环的支状荧光染料化合物, 2022-03-22, 中国, CN201910465139.6
(4) 仉华; 刘俊维; 牛慧玉; 王亚甫; 冯北斗; 王鑫; 一类荧光复合材料及其制备方法和应用, 2021-04-20, 中国, CN201811009990.X