常绪路 博士、副教授、博士生导师
常绪路,河南省优秀青年科学基金获得者、河南省高等学校青年骨干教师培养计划入选者。从事水产微生物资源与应用研究工作,主持国家自然科学基金、河南省优秀青年科学基金、河南省科技攻关等项目10余项。在国内外学术期刊《Journal of Hazardous Materials》、《Aquaculture》、《Fish & Shellfish Immunology》、《Probiotics and Antimicrobial Proteins》、《Aquaculture Reports》、《Aquaculture Nutrition》、《水产学报》等发表研究论文70余篇。主讲课程《微生物学》入选河南省本科一流课程、河南省第二批课程思政样板课程和河南省研究性教学示范课程,发表教改论文5篇,参编教材1部。
▊通讯地址
地址:河南省新乡市建设路河南师范大学东区实训楼211
邮编:453007
E-mail: changxulu@whu.edu.cn
电话:0373-3326639
▊教育背景
博士(2011/09-2016/06): 武汉大学,生命科学学院,微生物学专业
学士(2007/09-2011/06): 河南师范大学,生命科学学院,生物科学专业
▊工作经历
2022.02-至今,河南师范大学水产学院,副教授
2016.07-2022.01,河南师范大学水产学院,讲师
▊承担课程
1.微生物学、微生物实验、生物统计与试验设计 (本科)
2.生物统计学 (研究生)
▊研究方向
1. 水产微生物资源与应用
2. 水生动物肠道微生物与环境互作
▊科教项目
1. 表面蛋白BslA介导的鱼源贝莱斯芽孢杆菌肠道定植规律与机制研究, 国家自然科学基金-面上项目,2024-2027,立项在研,主持。
2. 表面蛋白BslA拮抗嗜水气单胞菌粘附定植黄河鲤肠道的作用效果与机制,河南省优秀青年科学基金,2025-2027,立项在研,主持。
3. 河南省高等学校青年骨干教师培养计划,2024-2026,立项在研,主持。
4. 凝结芽孢杆菌缓解镉暴露导致的鲤鱼肠道屏障损伤的作用及机制,国家自然科学基金-青年项目,2020-2022,结项,主持。
5. 贝莱斯芽孢杆菌抗菌肽Surfactin 在大口黑鲈疾病防控中的应用,河南省重点科技攻关项目,2023-2024,立项在研,主持。
6. 贝莱斯芽孢杆菌联合葡萄糖酸钠替代抗生素在黄河鲤健康养殖中的应用,新乡市科技攻关,2022-2023,立项在研,主持。
7. 凝结芽孢杆菌缓解镉暴露导致鲤鱼毒性损伤的作用与机制,河南省重点科技攻关项目,2020-2021,结项,主持。
8. 高效低温聚磷工程菌的构建及其在富营养化水体除磷中的应用,河南省重点科技攻关项目, 2019-2020,结项,主持。
9. 一株分离自北极的耐低温聚磷菌在水产养殖废水除磷中的应用,河南省高等学校重点科研项目,2018-2019,结项,主持。
▊研究成果
1. Chang Xulu; Yun Lili; Liu Zhikun; Shen Yihao; Feng Shikun; Yang Guokun; Meng Xiaolin*. Antagonistic effects and the underlying mechanisms of Bacillus velezensis and its antibacterial peptide LCI against Aeromonas hydrophila infection in Largemouth Bass. Probiotics and Antimicrobial Proteins, 2024, 10329
2. Chang Xulu; Shen Yihao; Yang Mingqi; Yun Lili; Liu Zhikun; Feng Shikun; Yang Guokun; Meng Xiaolin*; Su Xi*. Antipsychotic drug-induced behavioral abnormalities in common carp: The potential involvement of the gut microbiota-brain axis. Journal of Hazardous Materials, 2024, 472:134444
3. Wang Yawei; Huang Zhenyi; Gui Zewei; Yang Boya; You Fu; Yang Guokun; Zhang Xindang; Chang Xulu*; Meng Xiaolin*. Supplementation with Akkermansia muciniphila improved intestinal barrier and immunity in zebrafish (Danio rerio). Fish & Shellfish Immunology, 2024, 154: 109935
4. Yun Lili; Kang Meiru; Shen Yihao; Feng Junchang; Yang Guokun; Zhang Jianxin; Meng Xiaolin*; Chang Xulu*. Dietary Bacillus velezensis R-71003 and sodium gluconate improve antioxidant capacity, immune response and resistance against Aeromonas hydrophila in common carp. Fish & Shellfish Immunology, 2023, 139:108921
5. Chang Xulu*; Kang Meiru; Yun LiLi; Shen Yihao; Feng Junchang; Yang Guokun; Zhang Jianxin; Meng Xiaolin*. Sodium gluconate increases Bacillus velezensis R-71003 growth to improve the health of the intestinal tract and growth performance in the common carp (Cyprinus carpio L.). Aquaculture, 2023, 563(01):738980
6. Chang Xulu; Shen Yihao; Yun Lili; Wang Xianfeng; Feng Junchang; Yang Guokun; Meng Xiaolin; Zhang Jianxin; Su Xi*; The antipsychotic drug olanzapine altered lipid metabolism in the common carp (Cyprinus carpio L.): Insight from the gut microbiota-SCFAs-liver axis, Science of The Total Environment, 2023, 856:159054
7. Zhang Jianxin; Huang Mengyuan; Feng Junchang; Chen Yongyan; Li Meng; Meng Xiaolin; Chang Xulu*. Effect of beneficial colonization of Bacillus coagulans NRS 609 on growth performance, intestinal health, antioxidant capacity, and immune response of common carp (Cyprinus carpio L.). Aquaculture Nutrition,2023:1451394
8. Kang Meiru; Su Xi; Yun Lili; Shen Yihao; Feng Junchang; Yang Guokun; Meng Xiaolin; Zhang Jianxin; Chang Xulu*. Evaluation of probiotic characteristics and whole genome analysis of Bacillus velezensis R-71003 isolated from the intestine of common carp (Cyprinus carpio L.) for its use as a probiotic in aquaculture. Aquaculture Reports, 2022, 25:101254
9. Chang Xulu*; Chen Yongyan; Feng Junchang; Huang Mengyuan; Zhang Jianxin; Amelioration of Cd-induced bioaccumulation, oxidative stress and immune damage by probiotic Bacillus coagulans in common carp (Cyprinus carpio L.), Aquaculture Reports, 2021, 20: 100678
10. Chang Xulu; Kang Meiru; Shen Yihao; Yun Lili; Yang Guokun; Zhu Lei; Meng Xiaolin; Zhang Jianxin; Su Xi*. Bacillus coagulans SCC-19 maintains intestinal health in cadmium-exposed common carp (Cyprinus carpio L.) by strengthening the gut barriers, relieving oxidative stress and modulating the intestinal microflora, Ecotoxicology and Environmental Safety, 2021, 228: 0-112977
11. Zhang Jianxin; Huang Mengyuan; Feng Junchang; Chen Yongyan; Li Meng; Chang Xulu*. Effects of dietary Bacillus licheniformis on growth performance, intestinal morphology, intestinal microbiome, and disease resistance in common carp (Cyprinus carpio L.) Aquaculture International, 2021, 29(3): 1343-1358
12.Chang Xulu; Wang Xianfeng; Feng Junchang; Su Xi; Liang Junping; Li Hui; Zhang Jianxin*. Impact of chronic exposure to trichlorfon on intestinal barrier, oxidative stress, inflammatory response and intestinal microbiome in common carp (Cyprinus carpio L.), Environmental Pollution, 2020, 259:113846
13.Chang Xulu; Liu Ping; Feng Junchang; Su Xi; Huang Mengyuan; Chen Yongyan; Zhang Jianxin*; Li Baohua*. Impact of chronic exposure to the ionic liquid ([C8mim][PF6]) on intestinal physical barrier, immunological barrier and gut microbiota in common carp (Cyprinus carpio L.), Environmental Research, 2020, 189:109919
14.Chang Xulu; Li Hui; Feng Junchang; Chen Yongyan; Nie Guoxing; Zhang Jianxin⁎. Effects of cadmium exposure on the composition and diversity of the intestinal microbial community of common carp (Cyprinus carpio L.), Ecotoxicology and Environmental Safety, 2019, 171: 92-98
15.Chang Xulu; Feng Junchang; Guo Xiangrui; Huang Mengyuan; Nie Guoxing; Zhang Jianxin*. Dietary supplementation with Rehmannia glutinosa affects the composition of intestinal microorganisms in common carp, Journal of Basic Microbiology, 2018, 58(12):1023-1032
▊获奖荣誉
1.首届高校大学生水产类创新实践能力大赛全国总决赛优秀指导教师
2. 2023年度河南师范大学优秀党务工作者
3. 2021年度河南师范大学急难险重先进个人
4.2020年度河南师范大学优秀共产党员
5.2018年度河南师范大学文明教师