教师简介
| 职务：无 职称：副教授 电子邮箱：zhxl929@126.com | |
个人简历 | ||
张杏丽，博士，副教授，博士生导师。主持国家自然科学基金青年基金/面上项目、国家博士后面上及河南省自然科学基金面上各1项。以第一/通讯作者在Environmental Science & Technology, Environment International，Journal of Hazardous Materials和《环境科学》等国内外环境类期刊发表学术论文17篇。 | ||
教育/工作经历 | ||
2024.03-至今 河南师范大学环境学院 副教授 2018.07-2024.02 河南师范大学环境学院 讲师 2014.09-2018.07 南开大学 环境科学与工程学院 博士 2011.09-2014.07 南开大学 环境科学与工程学院 硕士 2007.09-2011.07 河南农业大学 林学院 学士 | ||
研究领域 | ||
研究领域：污染物的环境过程、生态毒性及健康风险。重点方向包括：（1）颗粒污染物（人工纳米材料、微塑料）的环境行为、毒性效应机制及复合生态效应研究；（2）新型有机污染物的生物富集、代谢转化及健康风险。 聚焦水体环境，以小球藻和斑马鱼为典型模式生物，联合多组学（转录组、蛋白组及代谢组）技术揭示污染物的致毒分子机制。 | ||
主要学术及社会兼职 | ||
国家自然科学基金函评专家，环境领域期刊Journal of Hazardous Materials、Environmental Pollution、Ecotoxicology and Environmental Safety等审稿人。 | ||
科研项目情况 | ||
[1] 国家自然科学基金面上项目（42577304），典型含沙水体中微塑料的老化行为及其对黄河鲤生殖机能的影响研究，2026.01-2029.12，主持 [2] 国家自然科学基金青年基金项目（41907349），微塑料对有机磷阻燃剂生物跨代效应的影响及其分子机制研究，2020.01-2022.12，主持 [3] 中国博士后科学基金面上项目（2019M662499），胞外聚合物调控微塑料水环境行为及生物效应的机制研究，2019.12-2022.12，主持 [4]国家自然科学基金面上项目（42377280）, 纳米二硫化钼在氯化消毒过程中的转化及对其藻类毒性演变的影响研究. 2024.01-2027.12, 参与 | ||
代表性论文 | ||
[1]Zhang, X.,# Wang, R.,# Tang, M., Jin, C., Zhang, G., Zou, W.*Suboptimal thermal storage facilitates aging of bottle-sourced polyethylene terephthalate microplastics fueling hepatic steatosis through gut-liver axis disruption. Environmental Science & Technology 2026,60, 12, 9103−9116. [2]Zou, W., Xia, M., Jiang, K., Cao, Z., Zhang X.,* Hu, X. Photo−oxidative degradation mitigated the developmental toxicity of polyamide microplastics to zebrafish larvae by modulating macrophage−triggered proinflammatory responses and apoptosis. Environmental Science & Technology 2020, 13888−13898. [3] Zhang, X., Zhou, Q., Zou, W., Hu, X.* Molecular mechanisms of developmental toxicity induced by graphene oxide at predicted environmental concentrations. Environmental Science & Technology 2017, 51, 7861−7871. [4] Zhang, X. Xia, M., Zhao, J., Cao, Z., Zou, W.,* Zhou, Q. Photoaging enhanced the adverse effects of polyamide microplastics on the growth, intestinal health, and lipid absorption in developing zebrafish. Environment International 2022,158, 106922. [5]Zhang, X., Shi, J., Wang, R., Ma, J., Li, X., Cai, W., Li, T., Zou, W.* Acute exposure to tris(2,4-di-tert-butylphenyl) phosphate elicits cardiotoxicity in zebrafish (Danio rerio) larvae via inducing ferroptosis. Journal of Hazardous Materials 2024，471, 134389. [6] Zhang, X., Shi, J., Yuan, P., Li, T., Cao, Z., Zou, W.* Differential developmental and proinflammatory responses of zebrafish embryo to repetitive exposure of biodigested polyamide and polystyrene microplastics. Journal of Hazardous Materials 2023, 460, 132472. [7] Zhang, X.,* Zhao, J., Gan, T., Jin, C., Li, X., Cao, Z., Jiang, K., Zou, W.* Aging relieves the promotion effects of polyamide microplastics on parental transfer and developmental toxicity of TDCIPP to zebrafish offspring. Journal of Hazardous Materials 2022, 437, 129409. [8] Zhang, X.,* Xia, M., Su, X., Yuan, P., Li, X., Zhou, C., Wan, Z., Zou, W.* Photolytic degradation elevated the toxicity of polylactic acid microplastics to developing zebrafish by triggering mitochondrial dysfunction and apoptosis. Journal of Hazardous Materials 2021, 413,125321 (ESI高被引论文). [9] Zou, W.,* Ma, S., Ma, H., Zhang, G., Cao, Z., Zhang, X.* Componential and molecular-weight-dependent effects of natural organic matter on the colloidal behavior, transformation, and toxicity of MoS2 nanoflakes. Journal of Hazardous Materials 2023, 459,132186. [10] Zou, W.,* Huo, Y., Zhang, X.,* Jin, C., Li, X., Cao, Z. Toxicity of hexagonal boron nitride nanosheets to freshwater algae: Phospholipid membrane damage and carbon assimilation inhibition. Journal of Hazardous Materials 2024, 465, 133204. [11] Zhang, X., Zou, W., Mu, L., Chen, Y., Ren, C., Hu, X.,* Zhou, Q.* Rice ingestion is a major pathway for human exposure to organophosphate flame retardants (OPFRs) in China. Journal of Hazardous Materials 2016, 318, 686–693. [12] Zou, W., Zhang, Y., Zhang, X.*, Zhang, G., Li, X., Jin, C., Cao, X. Interactions of monolayer molybdenum disulfide sheets with metalloid antimony in aquatic environment: Adsorption, transformation, and joint toxicity. Science of the Total Environment 2024, 926, 171937. [13] Zhang, X., Zhou, Q.,* Li, X., Zou, W., Hu，X. Integrating omics and traditional analyses to profile the synergistic toxicity of graphene oxide and triphenyl phosphate. Environmental Pollution 2020, 263, 114473. [14] Zou, W.; Chang, Y.; Wang, J.; Zhang, X.; Jin, C.; Wang, J.; Zhang, G.; Ouyang, S.; Cao, Z.; Zhou, Q. Biotransformation of atmospheric-Aged metal-sulfide nanosheets in respiratory tract fluids potentiates ferroptosis toward alveolar macrophages. Environmental Science & Technology 2026, 60, 7, 5310-5323 [15] Zou, W., Zhao, C., Zhang, X., Jin, C., Jiang, K., Zhou, Q.* Mitigation effects and associated mechanisms of environmentally relevant thiols on the phytotoxicity of molybdenum disulfide nanosheets. Environmental Science & Technology 2022, 55, 9556-9568. [16]Zou, W., Wan, Z., Zhao, C., Zhang, G., Zhang, X., Zhou, Q.* Impact of algal extracellular polymeric substances on the environmental fate and risk of molybdenum disulfide in aqueous media. Water Research 2021, 205, 117708. [17] Zou, W., Li, X., Li, C., Sun, Y., Zhang, X., Jin, C., Jiang, K., Zhou, Q., Hu, X.* Influence of Size and Phase on the biodegradation, excretion, and phytotoxicity persistence of single-layer molybdenum disulfide. Environmental Science & Technology 2020, 54, 19, 12295−12306. [18] Zou, W., Zhou, Q., Zhang, X., Hu, X.* Dissolved oxygen and visible light irradiation drive the structural alterations and phytotoxicity mitigation of single-layer molybdenum disulfide. Environmental Science & Technology 2019, 53, 7759−7769 [19] Zou, W., Zhou, Q., Zhang, X., Hu, X.* Environmental transformations and phytotoxicity of single layer molybdenum disulfide regulated by human acid. Environmental Science & Technology 2018, 52, 2638−2648. [20] 张杏丽,* 史菁, 赵静宜, 金彩霞, 张国庆, 邹威*. 环境浓度微塑料增强TDCIPP 肝脏毒性及其分子响应机制. 生态毒理学报 2023, 18(4), 384-400. [21] 张杏丽, 邹威，周启星*. 基于代谢组学技术分析磷酸三苯酯诱导斑马鱼胚胎发育毒性的分子机制.生态毒理学报 2019, 3, 79-89. [22] 张杏丽, 邹威，周启星*. 镉-八氯代二苯并呋喃复合污染土壤中紫茉莉对镉的修复能力. 环境科学2015, 8, 3045-3055. [23] 张杏丽, 周启星*. 土壤环境多氯二苯并二噁英/呋喃（PCDD/Fs）污染及其修复研究. 生态学杂志2013, 32,1054-1064. | ||
授权发明专利 | ||
无 | ||
荣誉与奖励 | ||
[1] 河南省优秀硕士学位论文指导教师（2024年度） [2] 河南师范大学科技创新“优秀指导教师”（2022年度） [3] 河南师范大学环境学院青年教师教学比赛“一等奖”(2022年度) [4] 河南师范大学优秀学位论文指导教师 (2023年度) [5] 指导硕士研究生获得国家奖学金2人次（2022和2023年度） | ||
