| 教育与工作经历: 2014.04-至今 河南师范大学,化学化工学院,教师 2008.9-2013.6 武汉大学化学与分子科学学院, 获理学博士学位 2004.9-2008.6河南师范大学化学与环境科学学院,获理学学士学位 主讲课程: 《药剂学》,《药剂学实验》,《工程伦理》 研究领域与兴趣:
纳米材料的设计合成、药物传递系统 年来主持的主要科研项目:
河南省高等学校重点科研项目:生物可降解聚碳酸酯前药载体的设计、合成及性能研究,项目编号:15A150053,2015.01-2016.12,2万元 新乡市科技攻关项目:生物可降解聚碳酸酯在改善紫杉醇类药物水溶性中的应用,项目编号:ZG15005,2014.01-2016.12,5万元 河南师范大学国家级科研项目培育基金:聚碳酸酯前药的设计、合成及靶向性能研究,项目编号:校20180085,2017.1-2019.12,6万元 河南师范大学青年科学基金项目:基于生物可降解聚碳酸酯前药载体的合成及靶向性能研究,项目编号:校20180146,2015.1-2017.12,3万元
代表性论文与专利:
Yanwei Chi, Zhiying Wang, Jie Wang, Wenpei Dong, Pengyang Xin, Jingjing Bi, Tao Jiang*, Chang-Po Chen*, Dimeric camptothecin-loaded mPEG-PCL nanoparticles with high drug loading and reduction-responsive drug release. Coloid and Polyer Science,2020, 298, 51–58. Tao Jiang, Xin Wang, Ge Wang, Yafu Wang, Kui Wang, Xiaopeng Xuan, Changpo Chen*, Kai Jiang, Hua Zhang*. Light-activated cycle-reversible intramolecular charge transfer fluorescent probe: monitoring of pHi trace change induced by UV light in programmed cell death, Chem. Commun.2019, 55,5279-5282. Pengyang Xin*, Huiyuan Kong, Yonghui Sun, Lingyu Zhao, Haodong Fang, ,Haofeng Zhu, Tao Jiang, Jingjing Guo, Qian Zhang, Wenpei Dong, Chang-Po Chen* Artificial K+ Channels Formed by Pillararene-Cyclodextrin Hybrid Molecules: , Tuning Cation Selectivity and Generating Membrane Potential. Angewandte Chemie International Edition. 2019, 58(9): 2779-2784. Pengyang Xin, * Yonghui Sun, Huiyuan Kong, Yaodong Wang, Si Tan, Jingjing Guo, Tao Jiang, Wenpei Dong,* Chang-Po Chen*. A unimolecular channel fromed by dual helical peptide modified pillar[5]arene: correlating transmembrane transport properties with antimicrobial activity and haemolytic toxicity Chem. Comm. 2017, 53, 11492-11495
Pengyang Xin,* Si Tan, Yonghui Sun, Qiaojv Ren,Wenpei Dong, Jingjing Guo, Tao Jiang and Chang-Po Chen*One-pot formation of hydrazide macrocycles with modified cavities: an example of pH-sensitive unimolecular cation channels Chem. Comm. 2017, 52, 5322-5325. Hua Zhang* , Caixia Wang , Tao Jiang , Haiming Guo* , Ge Wang , Xinhua Cai , Lin Yang , Yi Zhang , Haichuan Yu , Hui Wang , and Kai Jiang .Microtubule-Targetable Fluorescent Probe: Site-Specific Detection and Super-Resolution Imaging of Ultratrace Tubulin in Microtubules of Living Cancer Cells. Analytical Chemistry.2015, 87, 5216-5222. Hua Zhang*,Jiangli Fan,Kui Wang,Jing Li,Caixia Wang,Yamin Nie,Tao Jiang, Huiying Mu,Xiaojun Peng,and Kai Jiang.Highly Sensitive Naphthalene-Based Two-Photon Fluorescent Probefor in Situ Real-Time Bioimaging of Ultratrace Cyclooxygenase‑2 inLiving Biosystems. Analytical Chemistry.2014, 86, 9131-9138. Tao Jiang, Feng He, Renxi Zhuo. Synthesis,characterization and enzymatic degradation of novel biodegradable copolymers of5-allyloxy-1,3-dioxan-2-one with ε-caprolactone. Polymer Degradation andStability. 2013, 98(1), 325-330. Tao Jiang, Youmei Li, Yin Lv, YinjiaCheng, Feng He and Renxi Zhuo. Amphiphilic polycarbonate conjugates ofdoxorubicin with pH-sensitive hydrazone linker for controlled release. Colloidsand Surfaces B: Biointerfaces. 2013, 111, 542-548. Tao Jiang, Youmei Li, Yin Lv, YinjiaCheng, Feng He, Renxi Zhuo Amphiphilic Block-Graft copolymers based onPoly(ethylene glycol)-b-(polycarbonates-g-polycarbonates) for Controlled Releaseof Doxorubicin. Journal of Materials Science-Materials in Medicine 2014, 25, 131-139. 郑晓明,蒋涛,贺枫. PNIPAM-b-聚碳酸酯温敏胶束的制备及用作药物控制释放载体的研究. 高分子学报,2011,8, 895-902 Feng He*, Changfang Wang, Tao Jiang, Bing Han, Renxi Zhuo. Poly[(5-methyl-5-allyloxycarbonyl-trimethylenecarbonate)-co-(5,5-dimethyl-trimethylenecarbonate)] with Grafted Polyethylenimine as Biodegradable Polycations forEfficient Gene Delivery. Biomacromolecules. 2010, 11, 3028-3035. Changfang Wang, Yanxin Lin, Tao Jiang, Feng He*, Renxi Zhuo.Polyethylenimine-grafted polycarbonates as biodegradable polycations for genedelivery. Biomaterials. 2009, 30, 4824-4832.
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