袁婕，博士，硕士生导师

E-mail：2021107@htu.edu.cn

教育经历：

 2008.09—2012.07，信阳师范学院，化学，学士。

2013.09—2016.07，中南大学，化学，硕士。

2016.09—2021.06，湖南大学，化学，博士

工作经历：

2021.07—至今，河南师范大学，讲师

主讲课程：

分析化学、新型探针及其生物医学应用

研究领域：

新型染料、探针、光诊疗试剂的构建及其在疾病诊疗中的应用

主持项目：

国家自然科学青年科学基金项目

中原青年博士后创新人才资助项目

河南省科技攻关项目

河南省高校重点科研项目

中国博士后面上项目

代表性论文：

 (1) Jie Yuan, Hanxue Yang, Wenhui Huang, Shilong Liu, Hua Zhang,* Xiaobing Zhang,* Xiaojun Peng.* Design strategies and applications of cyanine dyes in phototherapy,  Chemical Society Reviews, 2025, 54, 341-366.

 (2) Jie Yuan, Qian-Hui Zhou, Shuai Xu, Qing-Ping Zuo, Wei Li, Xing-Xing Zhang, Tian-Bing Ren, Lin Yuan,* and Xiao-Bing Zhang* Enhancing the Release Efficiency of a Molecular Chemotherapeutic Prodrug by Photodynamic Therapy, Angewandte Chemie, 2022, 61(33): e202206169.

 (3) Qian Liu,^⊥ Jie Yuan,^⊥ Renfeng Jiang, Longwei He, Xuefeng Yang, Lin Yuan,* and Dan Cheng.* γ-Glutamyltransferase-Activatable Fluoro-Photoacoustic Reporter for Highly Sensitive Diagnosis of Acute Liver Injury and Tumor, Analytical Chemistry, 2023, 95(3): 2062-2070

 (4) Rong Peng,^†,§Jie Yuan,^†,§ Dan Cheng,^†,§ Tianbing Ren,† Fangping Jin,† Ronghua Yang,‡ Lin Yuan,*,† and Xiaobing Zhang.† Evolving a unique red-emitting fluorophore with an optically tunable hydroxy group for imaging nitroreductase in cells, in tissues, and in vivo, Analytical Chemistry, 2019, 91(24): 15974-15981

 (5) Jie Yuan¹, Rong Peng¹, Dongdong Su², Xingxing Zhang¹, Hepeng Zhao³, Xiujuan Zhuang³, Mei Chen⁴, Xiaobing Zhang¹, Lin Yuan¹. Cell membranes targeted unimolecular prodrug for programmatic photodynamic-chemo therapy, Theranostics, 2021, 11(7): 3502-3511.

 (6) Jie Yuan, Rong Peng, Dan Cheng,^* Liang-Hua Zou,^* and Lin Yuan.^* Revealing minor pH changes of mitochondria by a highly sensitive molecular fluorescent probe, Chemistry-An Asian Journal, 2021, 16(4): 342-347

 (7) Jie Yuan, Tian-Bing Ren,* Shuai Xu, Chun-Jiang Wang, Xiao-Bing Zhang, and Lin Yuan.* A unique multifunctional luminescent probe for self-monitoring photodynamic therapy by detecting H2S in cancer cells, ACS Applied Bio Materials, 2021, 4(8): 6016-6022

 (8) Jie Yuan; Rong Peng; Dan Cheng; Liang-Hua Zou; Lin Yuan ; Revealing minor pH changes of mitochondria by a highly sensitive molecular fluorescent probe, Chemistry-An Asian Journal, 2021,

 16(4): 342-347

 (9) Tun Wu,^‡aJie Yuan,^‡a Bo Song,^b Yu-Sheng Chen,^c Mingzhao Chen,^a Xiaobo Xue,^a Qianqian Liu,^a Jun Wang,^a Yi-Tsu Chan ^c and Pingshan Wang.^a* Stepwise self-assembly of a discrete molecular honeycomb using amultitopic metallo-organic ligand, Chemical Communications, 2017, 53(50): 6732-6735

专利：

 (1) 一种半菁类粘度检测荧光探针及其制备方法和应用. 袁婕，刘世龙，仉华. 专利号：ZL202411747108.7

 (1) 一种反应型游离亚铁血红素特异性响应的小分子荧光探针及其合成方法和应用. 张晓兵，徐帅，袁婕，刘永超，宦双燕，袁林. 专利号：ZL201911356973.8