教授

李莉

发布时间:2024-03-19






姓    名:李莉

职    称:教授(硕士生导师)

办公电话:

电子邮箱:lizzie406@163.com








个人简介:

   莉,教授,承担《免疫学》、《人体组织解剖学》的理论课和实验课教学,曾获河南省教育系统教学技能竞赛一等奖、“河南省教学标兵”、省级教学成果二等奖,博士国家奖学金。

工作经历:

2003至今,河南师范大学生命科学学院

2016-2017,加拿大渥太华大学访问学者

研究领域:

鱼鳍再生的分子生物学。主要包括:

(1)通过组学分析发现与鱼鳍再生相关的基因/表达特征;

(2)研究某一(家族)基因对鱼鳍再生过程中某一阶段或通路的调控机制;

(3)以鱼鳍的再生和发育模式为参考,探寻肢体再生能力在脊椎动物进化中丢失的原因。

主要学术及社会兼职:

中国遗传学会会员

中国动物学会会员

主持或参加科研项目情况:

近年主持的项目:

 1.泥鳅鱼鳍再生过程中actinodin基因的功能解析,国家自然科学基金U1404330

 2.mmp13基因对鱼鳍再生过程鳍条重建的分子调控,河南省高等学校青年骨干教师培养计划2018GGJS042

 3.斑马鱼鱼鳍再生过程mmp13基因的功能解析及活性增强子鉴别,河南省自然科学基金面上项目202300410243

学术成果:

代表性论文:

  1. Xinya Liu; Chaonan Liang;Jiaiq Fan; Li Li (corresponding author). Polyvinyl chloride microplastics induce changes in gene expression and organ histology along the HPG axis in Cyprinus carpio var.larvae. Aquatic Toxicology 258 (2023)106483(二区)

  2. Xinya Liu; Chaonan Liang;Miao Zhou; Zhongjie Chang; Li Li (corresponding author). Exposure of Cyprinus carpio var. larvae to PVC microplastics reveals significant immunological alterations and irreversible histologicalorgan damage. Ecotoxicology and Environmental Safety 249 (2023) 114377(二区)

  3. Xiaohua Xia, Menghan Sun, Miao Zhou, Li Li (corresponding author). Polyvinyl chloride microplastics induce growth inhibition and oxidative stress in Cyprinus carpio var.larvae. Science of The Total Environment,2020:136479(一区)

  4. Li Li, Jing Zhang,Marie-Andrée Akimenko.Inhibition ofmmp13a during zebrafish fin regeneration disrupts fin growth, osteoblasts differentiation, and Laminin organization. Developmental Dynamics,2020,249:187–198  

  5. Li Li, Qian Xiao,Linlin Wang, Zhongjie Chang. Expression analysis of And4 during fin regeneration in Misgurnus anguillicaudatus provides insights into its function. Fish Physiology and Biochemistry,2019, 45:935-942

  6. Li Li, Linlin Wang,Jingya He, Zhongjie Chang. Expression of Hsp70 reveals significant differences between fin regeneration and inflammation in Paramisgurnus dabryanus. Fish and Shellfish Immunology,2017, 64:352-356(一区)

  7. Li Li,Zhai Shengna,Wang Lele,Si Songbo,Wu Hailan,Chang Zhongjie. Hsp60 in caudalfin regeneration from Paramisgurnus dabryanus : Molecular cloning and expression characterization. Fish and Shellfish Immunology,2014,36(2):401-408(一区)

  8. Li Li, Jingya He, Linlin Wang, Weihua Chen, Zhongjie Chang. Gene expression profiles of fin regeneration in loach (Paramisgurnus dabryanu). Gene Expression Patterns,2017, 25:124-130

  9. Li Li,Nan Ping,Zhai Shengna,Wang Lele,Si Songbo,Chang Zhongjie. Molecular cloning,characterization, and expression of hsp60 in caudal fin regeneration of Misgurnus anguillicaudatus. Molecular and Cellular Biochemistry,2014,387(1):143-150(二区)