史瑜

史瑜，2022年博士毕业于华南农业大学，2022年10月-2024年9月在华南农业大学从事博士后研究，同月被引进到河南师范大学生命科学学院工作，主要从事植物病原菌致病机理及病害防控的相关工作，其中以第一作者（包括共同一作）和通讯作者（包括共同通讯）在Molecular Plant Pathology、Chinese Chemistry Letters、 Journal of Agricultural and Food Chemistry、Bioorganic Chemistry和International Journal of Molecular Sciences等期刊发表SCI论文10篇（其中一区8篇），单篇最高影响因子9.4。

植物病原菌致病机制及病害防控

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1. 国家自然科学基金面上项目，2025-2028，在研，第一参与人。

2. 河南省自然科学基金青年项目，2025-2026，主持。

3. 河南师范大学博士科研启动经费支持课题，2025-2027，主持。

4. 河南省博士后科研项目资助经费，2025-2027，主持。

5. 湖北省重点实验室开放课题，2023-2025，结项。

6. 广东省微生物信号与作物病害防控重点实验室开放课题，2023-2025，结项。

代表性论文：

1. Yu Shi^#, Zhao-Sheng Zhang^#,Jiang Shao^#, Chen Fu, Lan-Tu Xiong, Zhaodong Li* and Zi-Ning Cui*.Photoinduced palladium-catalyzed 1,3-diene-selective fluoroalkylamination compounds as potential bactericidal agent against Xanthomonas oryzae pv.oryzae, Chin Chem Lett 2024,35(1): 108794.

2.  Yu Shi, Tianfang Cheng, Qing wei Cheang, Xiaoyan Zhao, Zhao-xun Liang, Linghui Xu* and Junxia Wang*. A cyclic di-GMP-binding adaptor protein interacts with a N5-glutamine methyltransferase to regulate the pathogenesis in Xanthomonas citri subsp.citri, Mol Plant Pathol 2024, 25(7): e13496. 

3.  Yu Shi^#, Lan-Tu Xiong^#,Hui Li^#, Wen-Long Li^#, Dylan O'Neill Rothenberg, Li-ShengLiao, Xin Deng, Gao-Peng Song^* and Zi-Ning Cui^*. ^[1]Derivative of cinnamic acid inhibits T3SS of Xanthomonas oryzae pv. oryzae through the HrpG–HrpX regulatory cascade, Bioorg Chem 2023, 141: 106871.

4.  Yu Shi, Xiaobei Yang, Xiaoxin Ye, Jiaying Feng, Tianfang Cheng, Xiaofan Zhou, Ding Xiang Liu, Linghui Xu* and Junxia Wang^*. The methyltransferase HemK regulates the virulence and nutrient utilization of the phytopathogenic bacterium Xanthomonas citri subsp. citri, Int J Mol Sci 2022,23 (7), 3931.

5.  Lu-Lu He; Lan-Tu Xiong; Xin Wang; Yu-Zhen Li; Jia-Bao Li; Yu Shi*; Xin Deng; Zi-Ning Cui^*. Application of Inhibitors Targeting the Type III Secretion System in Phytopath ogenic Bacteria.Chin Chem Lett 2025,36(4): 110044.

6. Jiang Shao^#, Zhi-Jun Zhang^#, Yu Shi^#,Wei-Qi Jiang, Faisal Siddique,Liangye Chen, Genyan Liu,Jiakai Zhu, Xiong-Fei Luo, Ying-Qian Liu^*, Jun-Xia An, Cheng-Jie Yang, Zi-Ning Cui^*. Application and mechanism of cryptolepine and neocryptolepine derivatives as T3SS inhibitors for control of bacterial leaf blight on rice. Journal of Agricultural and Food Chemistry, J Agric Food Chem 2024, 72(13):6988-6997. 

7. Liangye Chena^a,#, Junjie Weia^a,#, Ruitao Xu ^a,#, Zhao-Sheng Zhang^b,#, Di Zhu^a, Wanjun Li^a, Lian-Hui Zhang^a,*, Yu Shic,^*, Zi-Ning Cui^a,*. Design, synthesis, and biological evaluation of disulfides based on garlic extract against rice bacterial leaf blight caused by Pantoea ananatis. Pest Manag Sci 2025,共同通讯。

8. 陈良业，徐锐涛，蔡昀辰，史　瑜^#，崔紫宁^#。不同杀菌剂对水稻新致病菌菠萝泛菌 Pantoea ananatis 的防效研究。华南农业大学学报,2025, 46(4): 480-487。共同通讯。 

9. Aoyun Yi^#, Liangye Chen^#, Junjie Wei^#, Zhao-Sheng Zhang^#, Wanjun Li, Yu Shi*, Bo Wang, Xiangyun Wang*, Zi-Ning Cui^*. Synthesis and biological evaluation of disulfides based on garlic extract as type III secretion system inhibitors against Erwinia amylovora. J Agric Food Chem 2025, 73, 12582-12590,共同通讯。

10. Junjie Wei†, Liangye Chen†, Wanjun Li†, Aoyun Yi†, Wenlong Li, Yu Shi^*, Xiangyun Wang^*, Zi-Ning Cui^*. Inhibitory activity and mechanism of arylfuran thioesters containing 1,3,4 -thiadiazole against Erwinia amylovora. Pest Manag Sci 2025,共同通讯。

11. Zhao-Sheng Zhang^#, Zhe He^#, Yu Shi^#, Ming-Ming Guan^#, Di Zhu, Ya-Sheng Li, Xin Deng, Zi-Ning Cui^*. Structure-based discovery of symmetric disulfides from garlic extract as Pseudomonas aeruginosa quorum sensing inhibitors. J Agric Food Chem 2024, 72 (37), 20299-20307.

12. Zhang ZS, Zhao DS, Zhu D, Guan M, Xiong LT, He Z, Li Y, Shi Y, Xu ZL, Deng X, Cui ZN. Design, synthesis, and biological evaluation of asymmetrical disulfides based on garlic extract as pseudomonas aeruginosa pqs quorum sensing inhibitors. J Agric Food Chem 2025, 73(10): 5850-5859.

13. Jinxing Wei, Linghui Xu, Yu Shi, Tianfang Cheng, Wenlan Tan, Yongguo Zhao, Chunsheng Li, Xinyu Yang, Lejun Ouyang, Mingken Wei, Junxia Wang^* and Guangyuan Lu^*. Transcriptome profile analysis of Indian mustard (Brassica juncea L.) during seed germination reveals the drought stress-induced genes associated with energy, hormone, and phenylpropanoid pathways. Plant Physiology Biochemistry, 2023, 200,107750.

14. Tianfang Cheng, Qing wei Cheang, Linghui Xu, Shuo Sheng, Zhaoting Li, Yu Shi, Huiyan Zhang, Li Mei Pang, Ding Xiang Liu, Liang Yang, Zhao-xun Liang^* and Junxia Wang^*. A pilZ domain protein interacts with the transcriptional regulator HinK to regulate type VI secretion system in Pseudomonas aeruginosa, Journal of Biological Chemistry, 2024,1016,105741.

15. Zhao XY, Chen XY, Lei JJ, Feng JY, Dong YY, Shi Y, Xu LH^*, Wang JX^*. A three-component signaling system plays multiple roles in the pathogenicity of Xanthomonas citri subsp. citri. Phytopathology Research 2025, 7: 00320.

16. Zhe Zhou, Xiaozhen Wu, Jiayi Li, Yiyin Zhang, Yaohua Huang, Wenping Zhang, Yu Shi, Junxia Wang^* and Shaohua Chen^*. A novel quorum quencher, Rhodococcus pyridinivorans XN-36, is a powerful agent for the biocontrol of soft rot disease in various host plants. Biological Control, 2022,169,104889.

17. Wang, X., Liang, L., Shao, H., Ye, X., Yang, X., Chen, X., Shi, Y., Zhang, L., Xu, L., and Wang, J. Isolation of the novel strain bacillus amyloliquefaciens F9 and identification of lipopeptide extract components responsible for activity against Xanthomonas citri subsp. citri. Plants (Basel) 2022, 11, 457.

18. Jie Gao., Long-Long Yang.,Yi-Ran Wang.,Yue-Yan Zhao.,Yu Shi.,Shuai-Jie Wei.,Ning Chen., Yu-Lan Zhang.,Wu-Jun Gao.,Shu-Fen Li. MITE Annotation and Landscape in 207 Plant Genomes Reveal Their Evolutionary Dynamics and Functional Roles. Molecular Ecology Resources 2025。