符运栋, 男, 博士, 讲师；
联系方式：fuyundong@htu.edu.cn
教育经历：
2012年09月 – 2016年06月 重庆邮电大学 本科
2016年09月 – 2019年06月 郑州大学 硕士
2019年09月 – 2024年06月 郑州大学 博士
工作经历：
2024/12 - 至今 河南师范大学 抗病毒性传染病创新药物全国重点实验室
研究领域与兴趣：
机制导向的不对称催化；金属有机；靶向药物设计与合成；
近年来主持项目：
1. 国家自然科学基金——青年项目，在研，主持，30万；
2 河南师范大学抗病毒全国重点实验引导项目，在研，主持，10万；
3. 河南师范大学博士科研启动项目，在研，主持，20万；
代表性论文：
1 Fu, Yun-Dong; Zhang, Han; Li, Bei-Bei; Huang, Lihua*; Xiao, Xiao; Wang, Min-Can; Wei, Donghui*; Mei, Guang-Jian*; Azocarboxamide-enabled enantioselective regiodivergent unsymmetrical 1,2-diaminations. Nat. Commun., 2024, 15, 10225.
2 Fu, Yun-Dong; Gao, Xiang; Jia, Shi-Kun; Xiao, Xiao; Wang, Min-Can; Huang, Lihua*; Mei, Guan-Jian*; Catalyst-free racemic and H2O/CPA-catalyzed asymmetric regio-reversed domino processes of triketone enones with azlactones, Green Chem., 2023, 25, 5692-5697.
3 Fu, Yun-Dong; Huang, Ming-Jie; Guo, Jiawen; You, Ya-Zhen; Liu, Hong-Min; Huang, Li-Hua*; Yu, Bin*; Targeting histone demethylase KDM5B for cancer treatment, Eur. J. Med. Chem., 2020, 208, 112760.
4 You, Yazhen; Fu, Yun-Dong; Huang, Mingjie; Shen, Dandan; Zhao, Bing.; Liu, Hongmin; Zheng, Yichao; Huang, Lihua; Recent Advances of m6A Demethylases Inhibitors and Their Biological Functions in Human Diseases. Int. J. Mol. Sci., 2022, 23, 5815.
5 Huang, Ming-Jie; Guo, Jia-Wen; Fu, Yun-Dong; You, Ya-Zhen; Xu, Wen-Yu; Song, Ting-Yu; Li, Ran; Chen, Zi-Tong; Huang, Li-Hua*; Liu, Hong-Min*; Discovery of new tranylcypromine derivatives as highly potent LSD1 inhibitors . Bioorg. Med. Chem. Lett., 2021, 41, 127993.
6 Li, Ling-Yu; Peng, Jia-Di; Zhou, Wenjuan; Qiao, Hui; Deng, Xin; Li, Zhou-Hua.; Li, Ji-Deng; Fu, Yun-Dong; Li, Song; Sun, Kai*; Liu, Hong-Min*; Zhao, Wen*, Potent hydrazone derivatives targeting esophageal cancer cells. Eur. J. Med. Chem., 2018, 148, 359-371.
7 Sun, Kai; Peng, Jia-Di; Suo, Feng-Zhi; Zhang, Ting; Fu, Yun-Dong; Zheng, Yi-Chao*; Liu, Hong-Min*, Discovery of tranylcypromine analogs with an acylhydrazone substituent as LSD1 inactivators: Design, synthesis and their biological evaluation. Bioorg. Med. Chem. Lett., 2017, 27, 5036-5039.
8 Liu, Zhenzhen; Zhao, Taoqian; Li, Zhonghua; Sun, Kai; Fu, Yundong; Cheng, Ting; Guo, Jimin; Yu, Bin*; Shi, Xiaojing*; Liu, Hongmin*, Discovery of [1,2,3]triazolo[4,5-d]pyrimidine derivatives as highly potent, selective, and cellularly active USP28 inhibitors. Acta Pharm. Sin. B, 2020, 10, 1476-1491.