姓 名: | 夏晓华 | ||
职 称: | 副教授(硕导) | ||
办公电话: | 15836072251 | ||
电子邮箱: | xxhlpf@163.com | ||
个人简介: |
主讲本科生《遗传学》、《基因工程》和研究生《生物反应器工程》、《基因工程技术》、《模式鱼类遗传学》等课程,并指导多项大学生创新训练项目及大学生生命科学竞赛。主要从事水生动物免疫、动物性别分化及调控和水生生物生理生态等方面的研究。先后在SCI及核心以上期刊发表论文四十余篇,主持国家自然科学基金、科技厅项目、横向合作项目等。 |
研究领域: |
主要研究方向: 1. 水生生物免疫机制研究; 2. 水生生物性别决定和分化; 3.水生生物生态毒理学。 |
主要学术及社会兼职: |
中国遗传学会会员 中国动物学会会员 |
主持或参加科研项目情况: |
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学术成果: |
代表性论文: 1. Xiaohua Xia*, Ning Liang, Xiaoyu Ma, Lu Qin, Zhongjie Chang, Xiaowen Zhang*. Effect of dietary supplementation with Leuconostoc mesenteroides DH onthe antimicrobial capacity and overall health of juvenile loach (Misgurnus anguillicaudatus)[J].Aquaculture, 2024, 579: 740208. 2. Xiaohua Xia, Xiaoyu Ma, Ning Liang, Lu Qin, Weiran Huo, Yi Li*. Damageof polyethylene microplastics on the intestine multilayer barrier, blood cellimmune function and the repair effect of Leuconostoc mesenteroides DH in thelarge-scale loach (Paramisgurnus dabryanus)[J]. Fish and Shellffsh Immunology. 2024, 147: 109460. 3. Weiran Huo, Lu Qin, Wanwan Guo, Xiaowen Zhang, Qiyan Du, Xiaohua Xia*(通讯作者).PvMR1, a novel C-type lectin plays a crucial role in the antibacterial immune response of Paciffc white shrimp, Penaeus vannamei[J]. Fish and Shellffsh Immunology,2024, 145: 109346. 4. Liuen Wang, Meimei Zheng, Jisheng Liu, Zeyu Jin, Cui Wang, Miaomiao Gao, HongweiZhang, Xiaowen Zhang, Xiaohua Xia*(通讯作者). LDL acontaining C-type lectin mediates phagocytosis of V.anguillarum andregulates immune effector genes in shrimp[J].Fish and Shellffsh Immunology, 2024, 145: 109361. 5. Yi Li, Mengyuan Qin, Shuo Han, Yuqi Wang, Chao Gao, Wenfang Niu, Xiaohua Xia*(通讯作者).Elimination of Microcystis aeruginosa through Leuconostoc mesenteroides DH andits underlying mechanism[J].2024, Science of the Total Environment, 908: 168290. 6. Yi Li, Shuo Han, Yuqi Wang, Mengyuan Qin, Chengjin Lu, Yingke Ma, Wenqing Yang, Jiajia Liu, Xiaohua Xia*(通讯作者), Hailei Wang*.Autoinducer-2 promotes adherence of Aeromonas veronii through facilitating the expression of MSHA type IV pili genes mediated by c-di-GMP[J]. Appl Environ Microbiol. 2023,89(11): e0081923. 7. Xiaowen Zhang, Manli Shen, Cui Wang, Miaomiao Gao, Liuen Wang, Zeyu Jin, Xiaohua Xia*(通讯作者). Impact of aluminum exposure onoxidative stress, intestinal changes and immune responses in red swamp crayfish(Procambarus clarkii)[J].2023, Science of the Total Environment, 855: 158902. 8. Xiaohua Xia, Wanwan Guo, Xiaoyu Ma, Ning Liang, Xiangyu Duan, Peihan Zhang, Ying Zhang, Zhongjie Chang, Xiaowen Zhang*. Reproductive toxicity andcross-generational effect of polyethylene microplastics in Paramisgurnus dabryanus[J].Chemosphere,2023, 313: 137440. 9. Xiaohua Xia,Xiaoyu Ma, Ning Liang, Xiangyu Duan, Songyun Wang, Wanwan Guo, Zhongjie Chang*.QNZ exposure induces development toxicity and mechanisms of hatching inhibition in large-scale loach (Paramisgurnus dabryanus) embryos[J]. Ecotoxicology and Environmental Safety, 2023, 253: 114663. 10. Xiaowen Zhang, Zeyu Jin, Manli Shen,Zhongjie Chang, Guoying Yu, Lan Wang, XiaohuaXia*(通讯作者). Accumulation of polyethylene microplastics induces oxidative stress, microbiome dysbiosis and immunoregulation in crayfish[J].Fish and Shellfish Immunology, 2022, 125: 276-284. 11. Xiaohua Xia, Gaopeng Liu, Xiaoling Wu, Shuangshuang Cui, CongHui Yang, Qi-yan Du, Xiao-wen Zhang. Effects of Macleaya cordata extract on TLR20 and the proinflammatory cytokines in acute spleen injury of loach (Misgurnus anguillicaudatus) against Aeromonas hydrophila infection[J]. Aquaculture,2021, 544(299):737105. 12. Qingyu Sun, Wanwan Guo, Peijin Wang. Zhongjie Chang, Xiaohua Xia*(通讯作者), Qiyan Du. Toxicity of 2-methyl-4-chlorophenoxy aceticacid alone and in combination with cyhalofop-butyl to cyprinus carpio embryos[J]. Environmental Toxicology and Pharmacology, 2021, 87: 103697. 13. Xiaohua Xia,Menghan Sun, Miao Zhou, Zhongjie Chang, Li Li. Polyvinyl chloride microplastics induce growth inhibition and oxidative stress in Cyprinus carpio var.larvae[J]. Scienceof the Total Environment, 2020, 716: 136479. 14. XiaoWen Zhang, CongHui Yang, HongQuan Zhang, XinTong Pan, ZeYu Jin, HongWei Zhang, XiaoHua Xia*(通讯作者). A C-typelectin with antibacterial activity in weather loach, Misgurnus anguillicaudatus[J].Journal of Fish Diseases, 2020, 43(12): 1531–1539. 15. Peijin Wang, Ruyan Wan, Weiran Huo, Hui Dong, Zhongjie Chang, Xiaohua Xia*(通讯作者). Cytotoxicity, genotoxicity,oxidative stress, and apoptosis in HepG2 cells induced by the imidazole ionic liquid 1-dodecyl-3-methylimidazolium chloride[J]. Environmental Toxicology, 2020, 35(6): 665-672. 16. Peijin Wang, Qingyu Sun, Ruyan Wan, Qiyan Du, Xiaohua Xia*(通讯作者).Progesterone affects the transcription of genes in the circadian rhythm signaling and hypothalamic-pituitary-gonadal axes and changes the sex ratio incrucian carp (Carassius auratus)[J].Environmental Toxicology and Pharmacology, 2020, 77: 103378. 17. Xiaohua Xia,Peijin Wang, Ruyan Wan, Zhongjie Chang, Qiyan Du. Progesterone affects sexdifferentiation and alters transcriptional of genes along circadian rhythm signaling and hypothalamic-pituitary-gonadal axes in juvenile Yellow River Carp(Cyprinus carpio var.)[J].Environmental Toxicology, 2019, 34: 1255–1262. 18. Weiran Huo, Ruyan Wan, Peijin Wang, Linxia Zhang,Xiaohua Xia*(通讯作者),Molecular cloning, characterization of dax1 gene and its response toprogesterone in Misgurnus anguillicaudatus, Drug and Chemical Toxicology, 2019, 42: 6, 624-633. 19. Xiaohua Xia, Ruyan Wan,Peijin Wang, Weiran Huo, Hui Dong, Qiyan Du.Toxicity of imidazoles ionicliquid [C16mim]Cl to Hela cells[J]. Ecotoxicology and Environmental Safety, 2018, 162: 408–414. 20. Ruyan Wan, Xiaohua Xia*(通讯作者), Peijin Wang, Weiran Huo, HuiDong, Zhongjie Chang. Toxicity ofimidazoles ionic liquid [C16mim]Cl to HepG2 cells[J]. Toxicology in Vitro, 2018, 52: 1–7. 21. Xiaohua Xia, Peijin Wang,Ruyan Wan, Weiran Huo, Zhongjie Chang. Toxic effects of cyhalofop-butyl onembryos of the Yellow River Carp (Cyprinus carpio var.): Alters embryoshatching, development failure, mortality of embryos and apoptosis[J].Environmental science and pollution research. 2018, 25: 24305–24315. 22. Xiaohua Xia, Weiran Huo, Ruyan Wan, Peijin Wang, Linxia Zhang, Zhongjie Chang. Molecular cloning, characterization, and expression profiles of the Sox3 gene in Chinese loach Paramisgurnus dabryanus[J]. Evolution & Development, 2018, 20: 108-118. 23. Xiaohua Xia, Weiran Huo, Ruyan Wan, Peijin Wang, Zhongjie Chang. Cloning,characterization and function analysis of DAX1 in Chinese loach(Paramisgurnus dabryanus)[J]. Genetica, 2018,146: 487–496. 24. Xiaohua Xia,Ruyan Wan, Weiran Huo, Linxia Zhang, Xiaopei Xia, Zhongjie Chang. Molecular cloning and mRNA expression pattern of Sox4 in Misgurnus anguillicaudatus[J].Journalof genetics, 2018, 97(4): 869–877.
著作: 1.《遗传学实验》,第二版,科学出版社,国家级精品课程配套教材,副主编; 2.《基因工程》,第二版,科学出版社,参编; 3. 河南省《基因工程在线精品课程》,主讲。
专利: 1. 李祎;王海磊;夏晓华,一种利用黑曲霉去除水体中微塑料的方法,中国,CN202110426976.5。
奖励: 1. 河南省自然科学优秀学术论文一等奖; 2. 河南师范大学青年骨干教师; 3. 河南师范大学研究生优秀指导教师; 4. 全国大学生生命科学竞赛一等奖指导教师; 5. 河南省大学生生命科学竞赛一等奖优秀指导教师。 |